People

a b c d e f g h i j k l m n o p q r s t u v w x y z All
(Includes Name, Title, Research Interests)
Molecular and Cellular Developmental Biology
Research Interests:

The Cadigan lab is interested in signal transduction and gene regulation in Drosophila and mammalian cells. Much of our research is focused on the Wnt/beta-catenin signaling pathway, but we are also exploring other pathways involved in cell specification during development and human disease.

Sally Camper
Margery W. Shaw Distinguished University Professor of Human Genetics
Accepting New Students?
No
Research Interests:

Birth defects research, organogenesis, mouse models of human disease, neuroendocrine development and function, growth insufficiency 

Pharmacology
Research Interests:

We study pathways involved in preserving genome stability as well as mechanisms of resistance to cancer chemotherapy.  

Vern Carruthers
Professor of Microbiology and Immunology
Accepting new students?
Yes
DEI Statement:
The Carruthers lab looks forward to future opportunities to mentor aspiring young scientists pursuing research careers in biomedical research. We place high value on diversity and welcome all individuals regardless of their background, race, religion, gender and gender identity, political views, sexual orientation, or disabilities. We especially encourage dedicated and ambitious individuals who treat others with respect, kindness, inclusion, and understanding to join our team.
Trainings and Identities
MORE Mentor Training, Implicit Bias Training, Disability Awareness Training, Gender Bias or Discrimination Training, First Generation-Identified
Research Interests:

ESCRT, endocytosos, autophagy, genetics, infection

Mol. Integ. Physiol
Research Interests:

Signal transduction pathways used by cytokine receptors and JAK tyrosine kinases; molecular actions of growth hormone; role of SH2-B adapter proteins in regulation of the cytoskeleton, gene expression and cellular differentiation and survival.

Associate Professor of Surgery
Accepting new students?
Yes
DEI Statement:
Diversity of thought and culture is essential for discovery. I welcome collaborators of all cultures and stations in life and truly enjoy mix and match of cultures in the laboratory.
Trainings and Identitites:
Intercultural Training, URM- and Immigrant-Identified
Research Interests:

B cell responses to Transplantation. Co-evolution of TNFRSF13B polymorphisms with microbial adaptations. Immunotherapies. Mutable vaccines.

Molecular and Cellular Developmental Biology
Research Interests:

We are working on protein sorting and quality control in the yeast secretory pathway.

Mentor:
Dr. Yatrik Shah, co-mentor: Dr. Costas Lyssiotis
Joined CMB:
2020
Undergraduate Institution:
Emory University
Honors:
Phi Beta Kappa, HHMI EXROP fellowship
Service:
Editor for Journal of Emerging Investigators (JEI)
Research Interests:

Understanding the role of mitophagy in colon cancer iron regulation, and investigating metabolic regulations of ER-mitochondria contact sites in cancer.

Internal Medicine
Research Interests:

The Role of Nuclear Receptors in Obesity/Diabetes-Related Cardiovascular Complications.

Associate Professor of Internal Medicine, Hematology-Oncology
Accepting new students?
Yes
DEI Statement:
People of color, women and LGBTQ are historically and presently marginalized in our society, including in the laboratory. Working in science will produce better results when the inequalities, differences, and conflicts between groups are recognized, addressed and effectively managed by all lab members.
Research Interests:

T-cell leukemia, T-cell development, Notch, transcriptional genomics, protein-protein interactions

Michigan Center for Translational Pathology
Research Interests:

Dr. Chinnaiyan's laboratory has focused on functional genomic,proteomic and bioinformatics approaches to study cancer for the purposesof understanding cancer biology as well as to discover clinicalbiomarkers. He and his collaborators have characterized a number ofbiomarkers of prostate cancer including AMACR, EZH2 and hepsin. AMACRis being used clinically across the country in the assessment of cancerin prostate needle biopsies.

Biological Chemistry
Research Interests:

My lab is mainly focusing on biochemical and structural studies on kinetochore assembly, histone chaperones, and Sestrin-mediated mTORC1 regulation.

Mentor:
Ann Miller
Joined CMB:
2017
Undergraduate Institution
Eastern Michigan University
Honors:
NSF Graduate Research Fellowship Recipient (2017)
Service:
Science Communication Fellowship with UM’s Museum of Natural History, Females Excelling More in Math, Engineering, and Science (FEMMES), Lean in for Graduate Students, Association for Women in Science, CMB Career Committee.
Research Interests:

Using optogenetics, investigate the spatiotemporal regulation of small GTPase RhoA and how it orchestrates actin cytoskeletal dynamics responsible for junctional remodeling and cytokinesis in vertebrate epithelial tissues.

Internal Medicine
Research Interests:

Our lab is interested in the proteolytic ECM remodeling of adipose tissues in development and obesity. Using 3-D adipocyte differentiation model and a series of genetically modified mice, we aim to define a molecular mechanism that links ECM remodeling to the regulation of organ function in development and diseases.

Assistant Professor of Biological Chemistry
Accepting new students?
Yes
DEI Statement:
I am committed to training and educating a diverse cadre of students, post-doctoral fellows, and researchers to build a diverse community of scientists that will be able to tackle the challenges of the 21st century.
Trainings and Identities:
MORE Mentor Training, Implicit Bias Training, Bystander Training, Gender Bias or Discrimination Training, First Generation-Identified
Research Interests:

microtubule, motor proteins, cryo-EM

Josie Clowney
Assistant Professor of Molecular, Cellular, and Developmental Biology
Accepting new students?
Yes
DEI Statement:
I try to foster a culture of abundance in the lab and create an environment in which trainees are able to be their "whole selves." I am also working to increase equity in how undergraduates obtain research experience.
Trainings and Identities:
MORE Mentor Training, Bystander Training, HHMI Inclusive Mentoring Training
Research Interests:

development, olfaction, neural circuits, genome evolution, sexual dimorphism

Sam Collie
Joined CMB:
2021
Faculty Mentor:
Dr. Carole Parent
Undergraduate Institution:
Millsaps College
Research Interests:

Understanding the role of NETs in neutrophil-mediated immune functions as well as the intercellular signaling cascade surrounding this process. 

Internal Medicine/Micro and Imm
Research Interests:
Molecular Mechanisms of HIV Disease Pathogenesis.

 

Mentor:
Dr. Melanie Ohi
Joined CMB:
2020
Undergraduate Institution:
Truman State University
Research Interests:

 I am studying the H. pylori virulence factor vacuolating cytotoxin A (VacA). Using single-particle cryo-EM, I am determining VacA's pore-form and characterizing its membrane interactions. 

Professor, Department of Otolaryngology-Head and Neck Surgery
Research Interests:

The Corfas Laboratory is interested in understanding the roles that interactions between neurons and glia-the two fundamental cell types of the nervous system-play in nervous system development, function and maintenance and in defining the molecular signals that orchestrate these interactions.

Adele Correia
Joined CMB:
2021
Mentor:
Dr. Andrew Lieberman
Research Interests:

I study the mechanisms of neurodegeneration in Niemann-pick type C disease, an autosomal recessive lysosomal storage disorder

G. Carl Huber Professor and Chair, Cell & Developmental Biology
Accepting new students?
No
DEI Statement:
Diversity is essential to achieve success, viewed from a broad array of vantage points. My laboratory has a diverse roster, and strives for a culture of inclusiveness. I am also proud of the efforts and program that we have put in place in my home department, CDB, to improve diversity and climate and, moreover, I am also proud of the fact that we are aware of how much more we need to do. Importantly, I believe that it is eminently possible to be successful with regards to diversity, equity, inclusiveness and climate while pursuing our main mission as a unit, which is research, discovery, and training.
Trainings and Identities:
MORE Mentor Training, Implicit Bias Training, Gender Bias or Discrimination Training, Leading the department I chair, CDB, regarding DEI and climate issues., first-generation-identified (college graduate)
Research Interests:

Tissue homeostasis, cell differentiation, genetic skin diseases, cancer, nucleus

Pharmacology
Research Interests:

Our research seeks to manipulate signaling pathways in T cells to understand their behavior. We are especially interested in how T cell recognize and respond to antigen. By applying our findings in the setting of cancer we aim to develop new immunotherapy strategies.

 

Mentor:
Manoj Puthenveedu
Joined CMB:
2017
Undergraduate Institution:
Penn State University
Honors:
NSF GRFP awardee, ARCS foundation Pittsburgh Chapter award recipient.
Service:
Social committee (Carnegie Mellon), Graduate sciences teaching club (Carnegie Mellon)
Research Interests:

I study the biosynthetic trafficking of G-protein-coupled receptors (GPCRs). GPCR localization to the the cell surface is critical for functional coupling to both extracellular agonists and G-protein effectors on the plasma membrane. Despite the functional importance of GPCR localization to the plasma membrane, relatively little is known about the biosynthetic trafficking of these receptors to the cell surface. I would like to understand how the trafficking of these receptors to the cell surface is regulated and how we can target receptors to the surface to increase signaling.