People

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(Includes Name, Title, Research Interests)
Michael Imperiale
Microbiology and Immunology
Research Interests:

Our laboratory studies the molecular biology of the small DNA tumor virus, BK polyomavirus. BKPyV is a ubiquitous human pathogen that establishes a subclinical, persistent infection of the urinary tract during early childhood. In healthy individuals, the virus is excreted periodically into the urine but does not cause disease, but in renal and bone marrow transplant patients, the virus can cause severe and sometimes life threatening illnesses. We are interested in the interplay between viral and host factors that determine whether the virus will persist or replicate in the cell. On the...

Molecular and Integrative Physiology and the Internal Medicine
Research Interests:

Our laboratory investigates the function and regulation of nutrient/energy-sensing molecules such as mTOR and AMP kinase in the development of human diseases including cancer and metabolic disorders such as diabetic complications.

Lori Isom
Maurice H. Seevers Professor and Chair of Pharmacology
Accepting new students?
MORE Mentor Training, Implicit Bias Training, Allyship Training, Anti-Racism Training, Change It Up!, Disability Awareness Training, Bystander Training, Gender Bias or Discrimination Training
Trainings and Identities:
MORE Mentor Training, Implicit Bias Training, Allyship Training, Anti-Racism Training, Change It Up!, Disability Awareness Training, Bystander Training, Gender Bias or Discrimination Training
Research Interests:

We study the mechanisms of pediatric epileptic encephalopathy, sudden unexpected death in epilepsy (SUDEP), and cardiac arrhythmia linked to mutations in voltage-gated sodium channel genes. Experimental models in our lab include transgenic mouse lines and human patient-derived induced pluripotent stem cell neurons and cardiac myocytes.