People

a b c d e f g h i j k l m n o p q r s t u v w x y z All
(Includes Name, Title, Research Interests)
Carole Parent
Raymond and Lynne Ruddon Collegiate Professor of Cancer Biology and Pharmacology, Research Professor of the Life Sciences Institute
Accepting new students?
No
DEI Statement:
My academic activities provide a platform from which I strive to support DEI initiatives and practices. First, the trainees in my group come from diverse scientific and socio-cultural backgrounds, which provides a rich environment that enhances the scientific enterprise and code of conduct in the laboratory. Second, through my role as the Director of the Michigan Pioneer Postdoctoral Program - a program that supports the training of outstanding postdoctoral fellows in the setting of collaborative research projects involving 2-3 faculty PIs at the University of Michigan – I work to promote a robust professional development environment with a strong focus on inclusiveness and diversity. Third, as the Director of Admissions and Recruitment for the Pharmacology Graduate Program, I actively implement an inclusive and holistic review process with the goal of having well-represented and diverse cohorts. Finally, I participate and engage in various Departmental and University initiatives to raise awareness and establish policies related to DEI issues.
Trainings or Identities:
MORE Mentor Training, Implicit Bias Training
Research Interests:

cell migration, signaling, immune responses, cancer invasion

Cell and Developmental Biology
Associate Director of CMB
Research Interests:
Our laboratory investigates the formation and progression of pancreatic cancer, one of the most lethal human malignancies. We study embryonic signaling pathways, such as Hedgehog and Wnt, which are activated during pancreatic carcinogenesis. The Hedgehog signaling pathway is not active in healthy adult pancreas. However, in pre-malignant lesions and in invasive pancreatic cancer Hedgehog signaling becomes activated via overexpression of one of the ligands, Sonic Hedgehog (Shh).

 

Neurology
Research Interests:

Polyglutamine neurodegenerative disease; Spinocerebellar Ataxia type 3; RNA interference as potential therapy including studies of polyglutamine diseases and Alzheimer's disease; Protein quality control in normal brain function in disease.

Assistant Professor of Ophthalmology and Visual Science
Accepting new students:
Yes
DEI Statement:
I currently have trainees from a variety of backgrounds who are interested in many career avenues. All encourage all trainees to explore the multitude of workshops, networking, seminars, training sessions available to UM and the broader scientific community. I also feel it is important to continue to educate myself and improve my own mentorship style.
Trainings and Identities:
MORE Mentor Training, Implicit Bias Training, EMBO Laboratory Leadership Training
Research Interests:

Photoreceptor Cell Biology, Membrane Trafficking, Ciliogenesis, Inherited Retinal Disease

Lauren Perl
CMB Program Administrator
Mentor:
Pierre Coulombe, Ph.D.
Year:
2018
Service:
UCSF STEM Career Day ambassador; Center for Cellular Construction representative for Bay Area Science Festival; Marine Biological Laboratory representative for professional development Face-to-face Networking.
Honors:
Rackham Merit Fellowship; Benard L. Maas Foundation Endowed Medical Fellowship Fund; Genentech Foundation Dissertation, Research Initiative for Scientific Enhancement (RISE), and Maximizing Access to Research Careers (MARC), and a SBD Choose Development scholar;
Teaching:
MBL Embryology Course assistant; Assisted with lab demos and mentorship while participating in discussion of STEM related topics for local Carver Scholars from middles schools in the bay area.
Research Interests:

Using biochemical and microscopy approaches with cell culture and mouse models, I am fascinated to reveal nuclear Keratin’s role in DNA damage response mechanisms.

Mentor:
Billy Tsai
Year:
2018
Undergraduate Institution:
Hillsdale College
Research Interests:

Understanding how polyomaviruses exploit host cell machinery to enter the nucleus

Molecular and Integrative Physiology
Research Interests:

Our goal is to identify and investigate genetic mechanisms that are likely to be important for aging and age-related disease in humans by focusing on equivalent, conserved processes in the fruit fly, Drosophila melanogaster. Currently we are studying neuronally-expressed genes involved in linking diet, obesity, and immune function with aging and aging-related disease.

Lev Prasov
Assistant Professor of Ophthamology and Visual Sciences
Accepting new students?
Yes
DEI Statement:
We are committed to having a diversity and inclusive laboratory environment and appreciate perspectives from individuals of different backgrounds. Our human genetic studies are very collaborative and involve people with diverse backgrounds and all over the world.
Research Interests:

Genetics, eye disease, developmental disorders

MSTP Student
Mentor:
Sriram Venneti
Undergrad Institution:
Duke University
Research Interests:

Chromatin, transcription, cell differentiation, cancer

Manoj Puthenveedu
Director of CMB
Pharmacology, Associate Professor
Accepting New Students?
Yes
Research Interests:

The Puthenveedu lab studies how receptor signaling pathways are organized in the cell, focusing on GPCRs relevant to drug addiction. We investigate the exciting new idea that signaling is specified not just by the drug/receptor pair, but also by where in the cell the receptors are located. We use innovative microscopy and molecular genetic techniques to directly track receptor trafficking and function in real time in living cells. The long-term goal is to identify factors that will allow us to actively relocate receptors to specific sites in the cell to fine-tune signaling.