People

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(Includes Name, Title, Research Interests)
Associate Professor of Internal Medicine
Accepting New Students?
No
DEI Statement
Science, like all human endeavors, can only benefit from a diverse range of perspectives and backgrounds. I support the principles of diversity, equity, and inclusion in scientific training and practice.
Trainings and Identities:
Implicit Bias Training, Anti-Racism Training, Bystander Training
Research Interests:

virus-cell interaction, positive-strand RNA viruses, flaviviruses, cell biology of RNA virus infeciton

Greg Tall
Pharmacology
Research Interests:

G protein coupled receptors (GPCRs) activate heterotrimeric G proteins to control myriad signaling pathways and physiological processes. Our lab broadly studies these signaling circuits with current emphasis on delineating the function of adhesion GPCRs and Ric-8 proteins (folding chaperones for all G protein alpha subunits).  Adhesion GPCRs appear to couple extracellular shear force events to intracellular G protein signaling.  We use a wide range of approaches, including purified protein structure/function, cell culture models, GPCR drug screening, and transgenic animal models. 

Professor of Microbiology and Immunology
Accepting new students?
Yes
Research Interests:

Retroviruses RNA HIV epigenetics

Molecular mechanisms of disease
Research Interests:

We study nucleotide repeat expansions as both mediators of normal neuronal function and drivers of neurologic diseases such as Fragile X Syndrome, FXTAS, ALS, and Frontotemporal Dementia. We use Drosophila, human neurons, biochemical approaches and next gen sequencing to define the mechanisms by which repeats cause disease and develop novel therapeutics. Recent work has focused on both alternative modes of protein translation and the biology repeat containing RNAs. Visit our Lab Webpage

Biological Chemistry
Research Interests:

Our laboratory is interested in elucidating the molecular mechanisms underlying chromatin modifications that regulate gene expression and other chromatin-associated functions. Our studies are primarily focused on the enzymes that dynamically control the methylation status of lysines in histones and non-histone proteins using structural and biochemical approaches.

CMB Mentor:
Jillian Pearring
Year:
2016
Honors:
Rackham Merit Fellowship
Research Interests:

Studying the photoreceptor specific role of the transition zone in ciliogenesis and outer segment formation.

Assistant Professor of Molecular and Integrative Physiology
Accepting new students?
Yes
Trainings and Identities:
Implicit Bias Training, Intercultural Training
Research Interests:

The Truttmann laboratory studies molecular chaperone functions in the context of proteostasis, aging and aging-associated diseases (e.g. Alzheimer’s disease, Huntington’s disease, Ataxias, etc.). We are particularly interested in the regulation and functions of heat shock protein 70 (Hsp70) family proteins (e.g. HSC70, Grp78/BiP, etc.). We employ numerous genetic, biochemical as well as behavioral approaches in conjunction with several model systems (tissue culture, Caenorhabditis elegans, mice, primary human tissue) to address our research questions in a holistic fashion.

CDB
Research Interests:

The Tsai laboratory is interested in clarifying the cellular entry pathways of a bacterial toxin (cholera toxin) and a DNA tumor virus (polyomavirus). Specifically, we wish to identify the host factors hijacked by these toxic agents during the course of infection, and to illuminate the molecular nature of the host-pathogen interactions.

Mentor:
Peter Todd, M.D., Ph.D.
Year:
2018
Undergraduate Institution:
Tunghai University, Taiwan
Mentor:
Dr. Scott Leiser
Year:
2019
Undergraduate Institution:
Drexel University
Honors:
Senior Second Honors Award (Drexel University)
Service:
Representative of Rackham Student Government, Representative of Ann Arbor Student Advisory Committee
Research Interests:

Aging and stress response pathways