Interested in human ovarian folliculogenesis and fertility preservation
Investigating the function of paternally-inherited histones during early embryogenesis.
Developing a device to simultaneously measure NADH generation and oxygen consumption in mitochondria in order to investigate the role of metabolic intermediates in bioenergetics. The data collected will be used to develop a computer model of the system.
My research focuses on investigating Notch cofactors that may regulate Notch signaling in T-cell Acute Lymphoblastic Leukemia
Understanding the role of nuclear hormone receptors in the radiosensitization of breast cancers.
Using cell lines and neuronal models to investigate molecular mechanisms of Ubiquilin-2 (UBQLN2) regulation in normal cellular function and ALS caused by UBQLN2 mutations.
Understanding translation regulation of G4C2 repeat-containing transcripts in C9orf72-associated ALS/FTD.
Identification of novel non-histone substrates of methyltransferases as well as structural and functional characterization of KDM5 demethylases
Aging, Neuroscience, Behavior